Kidney Cancer Research

Role of Lymph Node Spread of Kidney Cancer

Dr Michael Blute is interested in the significance of lymph node positive kidney cancer and the impact of lymph node dissection. There is a debate among clinicians as to whether performing a lymph node dissection at the time of nephrectomy is beneficial to survival.  Often, patients with high risk or metastatic kidney cancer will not have lymph node involvement.  However, those with lymph node positive kidney cancer demonstrate similar poor survival to those with distant metastases.  Identifying biomarkers, by assessing kidney cancer tissue, to help detect patients who would benefit from a lymph node dissection would improve surgical decision making for surgeon and patient alike.

Need: funding to support study and purchase equipment

Involved Faculty:  Michael Blute, MD, Paul Crispen, MD, Jose Trevino, MD, Yehia Daaka, PhD

Role of Optical Imaging in Differentiating Cancerous From Benign Kidney Tumors

Dr. Li-Ming Su is interested in pursuing further studies using fiberoptic confocal laser endomicroscopy (CLE) to further his preliminary findings that this technology may serve as an optical “biopsy” in replacement for more invasive needle biopsies to differentiate cancerous from benign kidney tumors. CLE provides a real time, high resolution image generated by a tiny laser probe when in contact with the kidney tumor.

Need: funding to support study and purchase equipment

Involved Faculty:  Li-Ming Su, MD

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