Laparoscopy and Robotic Adrenalectomy

Adrenal tumors are relatively rare but can cause significant problems including hypertension, excessive sweating, palpitations, weight gain, headaches and other symptoms as a result of hormone production from the adrenal mass.

These “functional” or hormone-secreting tumors include pheochromocytoma, aldosteronoma, Cushing’s tumor and adrenal cancer. Other adrenal tumors are non-functional and therefore cause little to no symptoms. For patients diagnosed with adrenal tumors (Figure 1), laparoscopic and robotic adrenalectomy provides patients with a safe and minimally invasive technique for removal of an adrenal mass.

Examples of CT scans demonstrating adrenal tumors removed by robotic adrenalectomy.Examples of CT scans demonstrating adrenal tumors removed by robotic adrenalectomy.Figure 1.  Examples of CT scans demonstrating adrenal tumors removed by robotic adrenalectomy.

These minimally invasive approaches have the advantage of improved cosmesis, reduced pain, blood loss, and hospital stay, as compared to conventional open surgery with similar cure rates. In select patients with very larger tumors, laparoscopic and robotic adrenalectomy may not be feasible and therefore open adrenalectomy may be required.

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Our Surgeons

picture of dr canalesBenjamin K. Canales, MD, MPH
Department of Urology
Click here for Video Biography

Paul Crispen, M.D.Paul L. Crispen, MD
Pete and Carolyn Newsome Urologic Oncology Professorship
UF Health Cancer Center Associate Director for Clinical Research
Department of Urology
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Padraic G. O’Malley, MD
Associate Professor
Chief, Division of Urologic Oncology
Department of Urology
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picture of dr suLi-Ming Su, MD, FRCS(Glasg)
David A. Cofrin Endowed Chair of Urologic Oncology
Chairman, Department of Urology
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The Surgery

Laparoscopic and robotic adrenalectomy requires patients undergo a general anesthesia. While operative time varies from one individual to another, the average operating time is approximately 2-3 hours.

During laparoscopic adrenalectomy approximately 3 to 4 small keyhole (< 1cm) incisions are made in the abdomen (Figure 2), which allow the surgeon to insert a telescope (called laparoscope) and hand held surgical instruments into the abdomen through portals call trocars.

Trocar configuration for laparoscopic and robotic adrenalectomy
Figure 2. Trocar configuration for laparoscopic and robotic adrenalectomy (courtesy of Intuitive Surgical Inc, Sunnyvale, CA).

The laparoscope allows for 10X magnification of the operative field, allowing the surgeon to accomplish the surgical procedure with improved visualization and without placing his hands into the abdominal cavity.  The abdomen is filled with carbon dioxide gas to create a larger working space for the surgeon to accomplish the operation. This gas is later evacuated from the abdomen at the conclusion of the operation.

With the robotic technique, the da Vinci S Surgical Robotic System is assembled to the trocars prior to commencing the operation (Figure 3).

da Vinci robot assembled to the operating trocars Figure 3. da Vinci robot assembled to the operating trocars (courtesy of Intuitive Surgical Inc, Sunnyvale, CA).

With the operating surgeon seated a few feet away at the surgeon operating console, the robotic instrumentation is controlled by the surgeon in real time with highly precise motion scaling (Figure 4).

Operating room configuration for left robotic adrenalectomy
Figure 4. Operating room configuration for left robotic adrenalectomy (courtesy of Intuitive Surgical Inc, Sunnyvale, CA).

The surgeon controls 2-3 multi-jointed robotic instruments to accomplish the tasks of dissection, cauterization, cutting and suturing (Figure 5).

Multi-jointed robotic instruments allow the surgeon to operate within the body with the same facility as tiny human hands
Figure 5. Multi-jointed robotic instruments allow the surgeon to operate within the body with the same facility as tiny human hands.

In addition, the surgeon controls a stereoscopic lens which provides a three dimensional, high definition image of the anatomy. The affected adrenal gland is then dissected and exposed. The tumor, adrenal gland and surrounding fat are excised along with any visible surrounding lymph nodes, preserving the adjacent organs including the liver, spleen, bowels and kidney. Once the adrenal tumor is excised, it is immediately placed within a plastic sack and the mass is removed from the abdomen intact through one of the pre-existing abdominal incisions. Finally the skin incisions are closed using plastic surgery techniques to minimize scarring.

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Full Procedural Video

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Potential Risks and Complications

As with any major surgery, complications, although rare, may occur with laparoscopic and robotic adrenalectomy. Potential risks and complications with this operation include but are not limited to the following:

  • Bleeding: Blood loss during this procedure is typically less than 100 cc with the rare need for a blood transfusion (<2% of patients). If you are interested in autologous blood transfusion (donating your own blood) prior to your surgery, you must make your surgeon aware. This can be arranged locally in Gainesville, FL at the Civitan Regional Blood center or at your local Red Cross.
  • Infection: Although patients are given broad spectrum intravenous antibiotics immediately prior to surgery, infections of the urinary tract and skin incisions may still occur but are rare. If you develop any signs or symptoms of infection after the surgery (fever, drainage from or redness around your incisions, urinary frequency/discomfort, pain) please contact us at once.
  • Adjacent Tissue / Organ Injury: Although uncommon, adjacent organs and tissues may be injured as a result of your surgery. This includes the colon, bowel, vascular structures, kidney, nerves, muscles, spleen, liver, pancreas and gallbladder. If injury to your lung cavity occurs, a small chest tube may be required to evacuate air, blood, and fluid from around your lung, thus allowing your lung to expand and work properly.  On rare occasions, further surgery may be required to address unexpected injuries to adjacent organs.
  • Incisional Hernia: Because of the small laparoscopic incisions, hernias at these sites can rarely develop. In addition, larger incisions are closed carefully prior to the completion of your surgery to minimize the risk of hernias.
  • Conversion to Open Surgery: In the rare event of complications or due to difficulty in dissecting by means of laparoscopic or robotic surgery, conversion to open surgery is sometimes required. This could result in a larger standard open incision and possibly a longer recuperation period.

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What to Expect after Surgery

Immediately after the surgery you will be taken to the recovery room then transferred to your hospital room once you are fully awake and alert.

  • Postoperative Pain: Although most patients in the first few days after surgery experience mild pain at their incision sites, this is generally well controlled by use of intravenous pain medication, patient-controlled anesthesia pump, or oral pain medication provided by your nurse. You may experience some minor transient shoulder pain (1-2 days) related to the carbon dioxide gas used to inflate your abdomen during the laparoscopic surgery.
  • NauseaNausea is common following any surgery especially related to general anesthesia. This is usually transient and controlled by medication which can be administered on an as needed basis by your nurse.
  • Urinary Catheter: A urinary catheter (also called foley catheter) is placed to drain your bladder at the time of surgery while you are asleep. This is in efforts to monitor your urine output over the first day or so following surgery. This is generally removed by your nurse once you are walking comfortably. It is not uncommon to have blood-tinged urine for a few days after your surgery while your catheter is in place.
  • Diet: Your diet will be advanced slowly following surgery from liquids to solids as tolerated. It is often the case that your appetite will be poor for up to a week following surgery. In addition, your intestinal function is often sluggish due to the effects of surgery and general anesthesia. It is for these two reasons that we recommend taking only small amounts of liquids by mouth at any one time until you begin to pass flatus and your appetite returns. In the meantime, your intravenous catheter will provide the necessary hydration to your body as you oral intake improves.
  • Fatigue: Fatigue is quite common following surgery and should subside in a few weeks following surgery.
  • Incentive Spirometry: You will be expected to do some very simple breathing exercises to help prevent respiratory infections using an incentive spirometry device (these exercises will be explained to you by the nursing staff during your hospital stay). Coughing and deep breathing is an important part of your recuperation and helps prevent pneumonia and other pulmonary complications.
  • Ambulation: On the evening of surgery it is very important to get out of bed and begin walking with the supervision of your nurse or family member to help prevent blood clots from forming in your legs. You can also expect to have SCD’s (sequential compression devices) wrapped around your lower legs and calf area to prevent blood clots called deep vein thrombosis from forming in your legs. In the days that follow surgery, patients are advised to walk at least 4-6 separate times a day in the hallways. This serves to further reduce the change of deep vein thrombosis and speed the return of bowel function.
  • Constipation/Gas Cramps: You may experience sluggish bowels for several days following surgery as a result of the anesthesia. Suppositories and stool softeners are usually given to help with this problem. Taking a teaspoon of mineral oil daily at home will also help prevent constipation. Narcotic pain medication can also cause constipation and therefore patients are encouraged to discontinue any narcotic pain medication as soon after surgery as tolerated.
  • Hospital Stay: The length of hospital stay following robotic adrenalectomy is generally 1 day.

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What to Expect After Discharge from the Hospital

  • Pain Control:  For the majority of patients, one to two days of oral narcotic pain medication may be necessary after which Extra Strength Tylenol is usually sufficient to manage their pain.  Again, narcotics should be minimized to avoid constipation and over sedation.
  • Showering:  Patients can shower immediately upon discharge from the hospital allowing their incisions to get wet. Once out of the shower, pad your incision sites dry and avoid any heavy creams or lotions. Tub baths or hot tubs in the first 2 weeks are discouraged as this will allow for prolonged soaking of your incisions and increase the risk of infection. You may shower after returning home from the hospital. Your wound sites can get wet, but must be patted dry immediately after showering. Your surgeon may elect to place surgical “glue” on your skin after closing. This acts as a barrier to infection and will fall off over time. Alternatively, adhesive tape, called Steri-strips, may be placed across your incisions. These can be removed one week following surgery. The sutures underneath the skin will dissolve in 4-6 weeks.
  • Activity:  Walking 4-6 times a day for the first two weeks after surgery on a level surface is strongly encouraged as prolong sitting or lying can increase your risk of pneumonia and deep vein thrombosis. It is permissible to climb stairs. No heavy lifting or exertion for up to 4 weeks following surgery.  Patients may begin driving once they are off narcotic pain medication and have full range of motion at their waist. Most patients can return to full activity including work on an average 3-4 weeks after surgery.
  • Diet:  Patients may resume a regular diet as tolerated. One sign that alerts a patient to when a regular diet can be attempted is when the patient begins to pass flatus.
  • Follow-up Appointment Patients should make a follow-up appointment with their surgeon by contacting UF & Shands Medical Plaza Urology Clinic at 352.265.8240.  Your surgeon will let you know the timing and schedule of clinic visits following surgery.
  • Pathology Results: The pathology results from your surgery are usually available in one week following surgery. Your results will be discussed with you either by phone or directly in the office during a follow-up clinic appointment.

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Frequently Asked Questions (FAQs)

What is the advantage of laparoscopic and robotic adrenalectomy as compared to open surgery?

  • These minimally invasive laparoscopic techniques have translated into a significant benefit to patients including reduced blood loss and transfusions, reduced pain, shorter hospital stays, improved cosmesis, and a faster recovery as compared to open surgery. While open surgery requires either a large abdominal or flank incision, minimally invasive approaches involve 3-4 keyhole incisions in the abdomen.  Published outcomes of laparoscopic and robotic adrenalectomy demonstrate comparable cure rates to open surgery.

Are there potential disadvantages?

  • Most patients with adrenal tumors who are candidates for open surgery are also excellent candidates for a laparoscopic or robotic approach. These minimally invasive approaches have become the standard of care for most adrenal tumors. In general there are no particular disadvantages; however, some situations may dictate the need for open surgery (see below).

What patients are not good candidates for laparoscopic and robotic adrenalectomy?

  • Patients with very large tumors or tumors invading surrounding structures e.g. vena cava, kidney, liver, bowel may be best served by an open approach due to the extent and need for adjacent organ resection. Medical conditions such as severe lung and heart disease may not be able to tolerate a laparoscopic or robotic approach.

What is the difference between a laparoscopic and robotic approach?

  • Both are laparoscopic approaches and the choice of approach is a matter of surgeon preference. Operative times, blood loss, and hospital stays are similar between a pure laparoscopic and robotic technique. These procedures are performed by inflating the abdomen with carbon dioxide gas and placing a laparoscopic lens affixed to a high definition camera into the abdomen to view the internal organs. Conventional laparoscopic surgery involves hand held instruments, while robotic surgery involves the use of a sophisticated robotic device (called the da Vinci S Surgical Robotic System) with wristed instrumentation to allow the surgeon to dissect within the abdomen while controlling these instruments externally from a surgeon console.

What happens if complications arise and conversion to open surgery is required?

  • Although extremely rare, conversion to open surgery may be required if difficulty with dissection is encountered during the laparoscopic approach. Our surgeons are trained in open surgical approaches as well as laparoscopy and therefore are well equipped to complete the surgery in an open fashion if needed.

What is the overall success rate of laparoscopic and robotic adrenalectomy?

  • Success rate in complete removal of the adrenal tumor is similar to open surgical approaches.  Prognosis is generally excellent as most adrenal tumors are benign. In cases of adrenal cancer, further therapies may be required as these are generally aggressive cancers. The pathology report will be available one week following surgery and will reveal whether the tumor is benign or malignant.

Will I need further treatment such as radiation or chemotherapy following surgery?

  • As mentioned previously, most adrenal tumors are benign and therefore prognosis remains excellent as most are cured with surgery alone. Rarely, patients are found to have large, invasive cancers that may require adjuvant treatment under the advisement of a medical oncologist.

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